Reza Kheirandish; Vahid Sardar Mehni; Amin Reza Salari; Omid Azari
Volume 18, Issue 3 , September and October 2011, , Pages 158-165
Abstract
Background and Purpose: Mummy is the semi-solid material extracted from mountains in the south of Kerman province. It is used in traditional medicine as a remedy for inflammation، articular injuries، rheumatism، bone fracture، wound and back pain. In the present study، histopathological and geometrical ...
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Background and Purpose: Mummy is the semi-solid material extracted from mountains in the south of Kerman province. It is used in traditional medicine as a remedy for inflammation، articular injuries، rheumatism، bone fracture، wound and back pain. In the present study، histopathological and geometrical aspects of topical effects of the mummy on rabbit cutaneous wound healing were investigated. Methods and Materials: This experimental study was conducted on 5 white healthy rabbits. Six full thickness cutaneous wounds were created on the both sides of the vertebral column of each rabbit. Right side wounds were considered as control and the left side ones as cases (to use mummy). The cranial wounds (rectangular، 2.5×2.5 cm) were considered for geometrical evaluation and the middle and caudal wounds (made by 10mm punch) were considered for histopathological study. Data were analyzed using SPSS 16 using repeated measurement، analysis of variance and student t-test. P≤0.05 was considered as statistically significant. Results from the microscopic evaluation were compared as description of the group values. Results: The geometrical evaluation over a 4-week period demonstrated that wound healing percentage in the treatment group (100%) was significantly higher than the control group (94.5%±0.91) (P